Review Questions

A patient presents to his PCP with a 3 day history of fever, chest pain, and cough. He informs you that he recently went on a trip exploring caves in the midwest. The chronic form of this condition will lead to granulomas and cavitations in the upper lobes of the lungs. What do you expect to find upon histology?
A) pilot's wheel shaped fungus
B) thick walled cells showing broad based budding
C) acid fast bacteria
D) macrophages filled with many yeast-like cells
E) pleural cells showing a biphasic pattern (epithelioid cells and sarcomatoid cells)

A 50yo female with a history of asthma presents to the clinic complaining of white spots in her mouth. She explains that the spots started appearing ever since she started using Fluticasone. She is worried that this may be cancer, but you find that the spots can be scraped off. What does this organism do at 37 degrees Celsius?
A) forms yeast cells
B) unable to grow
C) cause pseudomembranes in the colon
D) leads to changes in vaginal pH
E) forms germ tubes

A 15yo male presents to the clinic with dyspnea. His IgE levels are elevated and CXR reveals bilateral migrating infiltrates. If we were to examine the organism under microscope, we'd see V-shaped branching. The patient has a condition that predisposes him to this condition. What mutation causes this condition?
A) VHL gene chromosome 3
B) COL4A5 gene X chromosome
C) CTFR gene chromosome 7
D) SERPINA1 gene chromosome 14
E) WT1 gene chromosome 11