Toxicology

1. Barbiturate Overdose
-alkanize urine-"ion trapping"

2. Benzodiazepine Overdose
-flumazenil-reverses toxicity

3. Alchohol
-intoxication-supportive care
-withdrawal-benzodiazepine, naltrezone, acamprostate, antabuse, clonidine

4. Phencyclidine Overdose
-benzodiazepines

5. LSD Overdose
-benzodiazepines and antipsychotics

6. Cocaine
-rhabdomyolysis-kidney cannot handle myoglobin-->sustained muscle contractions
-overdose-phentolamine and labetalol, acidify urine, supportive care (lorazepam and haloperidol)
-withdrawal-bromocriptine

7. Amphetamine
-overdose-cyproheptadine-serotonin blocker for serotonin syndrome
-withdrawal-bromocriptine

8. Methylxanthines
-toxicity-convulsions, arrhythmias, nausea, vomiting
-treat cardiac with beta-blocker

9. Nicotine
-smoking cessation-buproprion, varenicline